Lissandra vs Katarina Mid Matchup
Lissandra Mid wins 52.0% of 2,843 Low Elo games against Katarina Mid, +0.8 points vs expected, 2-patch window 26.19-26.20.
Researched on LoL patch 26.20. Tips are written to hold at any rank; stats come from Low Elo ranked games up to patch 26.20.
Why Lissandra is favored
Lissandra's point-blank root and targeted stun can stop Katarina's all-in, while her E helps her follow roams and set up ganks. This makes Lissandra a strong answer to Katarina's melee entry even when she cannot solo-kill her in lane.
Measured in High Elo: Lissandra wins 2.6pp more often than expected over 1,658 games.
How to play as Lissandra
Hold W or R for Katarina's entry and use the follow-up control to set up a gank; do not spend both tools before she commits.
Ring of Frost(W) roots nearby enemies and Frozen Tomb(R) stuns a target, so both can stop Katarina's channel or retreat.
Glacial Path(E) gives Lissandra a second activation to follow Katarina's roam or reposition away from Shunpo(E).
How to play as Katarina
Bait Lissandra's W and R before channeling Death Lotus, and keep E available to leave if she starts her crowd-control combo.
Sources
These notes come from r/LissandraMains, checked against the champions' abilities.