Yasuo & Syndra Synergy
Yasuo Mid and Syndra ADC win 54.4% of 923 Low Elo games together, +1.4 points vs expected, 2-patch window 26.19-26.20.
Researched on LoL patch 26.20. Tips are written to hold at any rank; stats come from Low Elo ranked games up to patch 26.20.
Why this duo works
Syndra's Scatter the Weak(E) displaces enemies into the airborne window Yasuo needs for Last Breath(R); if she pushes a Dark Sphere into the same target, its stun gives Yasuo more time to follow up. Syndra players specifically note Yasuo's fit with her displacement, giving the duo a coordinated pick and teamfight engage.
Measured in High Elo: this duo wins 2.7pp more often than expected over 1,053 games.
Playing the duo
Scatter the Weak(E) knocks enemies back, which counts as airborne for Last Breath(R); a target hit by a pushed Dark Sphere is also stunned.
How to play as Yasuo
Stay within Last Breath(R) range and cast as Syndra's E displaces a target; the window is brief, while a pushed sphere adds a stun for a more forgiving follow-up.
How to play as Syndra
Coordinate before using Scatter the Weak(E): aim its displacement toward Yasuo while he is in range to follow with Last Breath(R), and push a Dark Sphere into the target when possible to add the stun.
Sources
These notes come from LoL Wiki, leagueoflegends.com, and r/syndramains, checked against the champions' abilities.