Yorick vs Mordekaiser Top Matchup
Yorick Top wins 51.9% of 3,886 Low Elo games against Mordekaiser Top, +2.6 points vs expected, 2-patch window 26.19-26.20.
Researched on LoL patch 26.20. Tips are written to hold at any rank; stats come from Low Elo ranked games up to patch 26.20.
Why Yorick is favored
Yorick's Maiden of the Mist(R) now follows him into Mordekaiser's Realm of Death(R), so Mordekaiser cannot remove Yorick's main source of pet damage by isolating him. Yorick players identify this interaction as the reason the matchup shifted, while Yorick's E-marked ghouls add further pressure during the duel.
How to play as Yorick
Keep the Maiden active when Mordekaiser uses Realm of Death(R); she follows you inside now, so use that pressure while he is separated from his team. If an even all-in does not work, return to ranged E pressure and side-lane play rather than forcing repeated duels.
The Maiden of the Mist(R) follows Yorick into and out of Mordekaiser's Realm of Death(R), so Mordekaiser no longer gets a pet-free duel by isolating him.
Mourning Mist(E) marks its target and makes nearby Mist Walkers leap onto it, so landing E can quickly turn on ghoul pressure.
How to play as Mordekaiser
Sidestep Mourning Mist(E) before committing; if it marks you, the Mist Walkers leap in and add pressure. Also plan for the Maiden to follow Yorick into your Realm of Death(R).
Sources
These notes come from LoL Wiki, r/MordekaiserMains, and r/yorickmains, checked against the champions' abilities.