Best Cassiopeia Mid Synergies

Compare Cassiopeia Mid strongest and weakest synergies by duo win rate, expected win rate, delta, sample size, and allied role for team comp planning.

Updated 2026-09-20. Data is current for LoL patch 26.18 (all regions, low elo and high elo).

How these matchup statistics are calculated

Counter and synergy statistics use Ranked Solo/Duo games, exclude matches shorter than 600 seconds, and group results by patch window, region, rank scope, and champion role.

Pairwise pages use a rolling three-patch window and compare observed win rate with a log-odds expected win rate based on each champion's role-adjusted baseline; listed pairs require at least 500 games.

Read the full methodology for the model and guidance on interpreting these results.

Summary

Low Elo data lists Jarvan IV Jungle, Lucian ADC, Yunara ADC, Vayne ADC, Blitzcrank Support, Mordekaiser Top, Malphite Top, Nautilus Support, Tristana ADC, and Lulu Support as the strongest synergy partners for Cassiopeia Mid. The weakest listed synergies for Cassiopeia Mid are Teemo Top, Kayn Jungle, Warwick Jungle, Garen Top, Briar Jungle, Jhin ADC, Seraphine Support, Jinx ADC, Ezreal ADC, and Morgana Support. The detailed info below lists each partner with observed win rate, expected win rate delta, sample size, rank scope, and patch window.

Detailed info:

Top 10 Low Elo Cassiopeia Mid all-role strongest synergies

  1. Jarvan IV Jungle - Low Elo data: Cassiopeia Mid vs Jarvan IV Jungle, 52.4% observed win rate, +4.8 percentage points vs expected, 529 games, 3-patch window 26.16-26.18.
  2. Lucian ADC - Low Elo data: Cassiopeia Mid vs Lucian ADC, 49.3% observed win rate, +4.5 percentage points vs expected, 698 games, 3-patch window 26.16-26.18.
  3. Yunara ADC - Low Elo data: Cassiopeia Mid vs Yunara ADC, 51.0% observed win rate, +4.1 percentage points vs expected, 739 games, 3-patch window 26.16-26.18.
  4. Vayne ADC - Low Elo data: Cassiopeia Mid vs Vayne ADC, 49.8% observed win rate, +3.9 percentage points vs expected, 500 games, 3-patch window 26.16-26.18.
  5. Blitzcrank Support - Low Elo data: Cassiopeia Mid vs Blitzcrank Support, 51.4% observed win rate, +3.6 percentage points vs expected, 648 games, 3-patch window 26.16-26.18.
  6. Mordekaiser Top - Low Elo data: Cassiopeia Mid vs Mordekaiser Top, 51.5% observed win rate, +3.4 percentage points vs expected, 637 games, 3-patch window 26.16-26.18.
  7. Malphite Top - Low Elo data: Cassiopeia Mid vs Malphite Top, 52.1% observed win rate, +3.3 percentage points vs expected, 691 games, 3-patch window 26.16-26.18.
  8. Nautilus Support - Low Elo data: Cassiopeia Mid vs Nautilus Support, 49.2% observed win rate, +2.5 percentage points vs expected, 1,102 games, 3-patch window 26.16-26.18.
  9. Tristana ADC - Low Elo data: Cassiopeia Mid vs Tristana ADC, 49.9% observed win rate, +2.5 percentage points vs expected, 909 games, 3-patch window 26.16-26.18.
  10. Lulu Support - Low Elo data: Cassiopeia Mid vs Lulu Support, 49.1% observed win rate, +1.9 percentage points vs expected, 756 games, 3-patch window 26.16-26.18.

Top 10 Low Elo Cassiopeia Mid all-role weakest synergies

  1. Teemo Top - Low Elo data: Cassiopeia Mid vs Teemo Top, 45.1% observed win rate, -4.0 percentage points vs expected, 630 games, 3-patch window 26.16-26.18.
  2. Kayn Jungle - Low Elo data: Cassiopeia Mid vs Kayn Jungle, 45.1% observed win rate, -2.6 percentage points vs expected, 1,014 games, 3-patch window 26.16-26.18.
  3. Warwick Jungle - Low Elo data: Cassiopeia Mid vs Warwick Jungle, 46.9% observed win rate, -2.3 percentage points vs expected, 622 games, 3-patch window 26.16-26.18.
  4. Garen Top - Low Elo data: Cassiopeia Mid vs Garen Top, 46.4% observed win rate, -2.3 percentage points vs expected, 897 games, 3-patch window 26.16-26.18.
  5. Briar Jungle - Low Elo data: Cassiopeia Mid vs Briar Jungle, 48.0% observed win rate, -1.8 percentage points vs expected, 565 games, 3-patch window 26.16-26.18.
  6. Jhin ADC - Low Elo data: Cassiopeia Mid vs Jhin ADC, 45.1% observed win rate, -1.7 percentage points vs expected, 1,724 games, 3-patch window 26.16-26.18.
  7. Seraphine Support - Low Elo data: Cassiopeia Mid vs Seraphine Support, 47.0% observed win rate, -1.3 percentage points vs expected, 1,010 games, 3-patch window 26.16-26.18.
  8. Jinx ADC - Low Elo data: Cassiopeia Mid vs Jinx ADC, 48.2% observed win rate, -1.3 percentage points vs expected, 1,629 games, 3-patch window 26.16-26.18.
  9. Ezreal ADC - Low Elo data: Cassiopeia Mid vs Ezreal ADC, 42.2% observed win rate, -1.3 percentage points vs expected, 1,187 games, 3-patch window 26.16-26.18.
  10. Morgana Support - Low Elo data: Cassiopeia Mid vs Morgana Support, 46.8% observed win rate, -1.3 percentage points vs expected, 748 games, 3-patch window 26.16-26.18.

Top 10 High Elo Cassiopeia Mid all-role strongest synergies

  1. Zeri ADC - High Elo data: Cassiopeia Mid vs Zeri ADC, 57.5% observed win rate, +5.6 percentage points vs expected, 602 games, 3-patch window 26.16-26.18.
  2. Blitzcrank Support - High Elo data: Cassiopeia Mid vs Blitzcrank Support, 55.9% observed win rate, +4.8 percentage points vs expected, 558 games, 3-patch window 26.16-26.18.
  3. Qiyana Jungle - High Elo data: Cassiopeia Mid vs Qiyana Jungle, 53.4% observed win rate, +3.5 percentage points vs expected, 653 games, 3-patch window 26.16-26.18.
  4. Jax Top - High Elo data: Cassiopeia Mid vs Jax Top, 52.9% observed win rate, +3.5 percentage points vs expected, 571 games, 3-patch window 26.16-26.18.
  5. Tristana ADC - High Elo data: Cassiopeia Mid vs Tristana ADC, 54.9% observed win rate, +3.4 percentage points vs expected, 883 games, 3-patch window 26.16-26.18.
  6. Ashe ADC - High Elo data: Cassiopeia Mid vs Ashe ADC, 53.2% observed win rate, +2.9 percentage points vs expected, 530 games, 3-patch window 26.16-26.18.
  7. Bard Support - High Elo data: Cassiopeia Mid vs Bard Support, 52.2% observed win rate, +2.9 percentage points vs expected, 632 games, 3-patch window 26.16-26.18.
  8. Camille Top - High Elo data: Cassiopeia Mid vs Camille Top, 53.7% observed win rate, +2.3 percentage points vs expected, 503 games, 3-patch window 26.16-26.18.
  9. Lee Sin Jungle - High Elo data: Cassiopeia Mid vs Lee Sin Jungle, 51.3% observed win rate, +2.2 percentage points vs expected, 1,562 games, 3-patch window 26.16-26.18.
  10. Pyke Support - High Elo data: Cassiopeia Mid vs Pyke Support, 50.9% observed win rate, +2.0 percentage points vs expected, 670 games, 3-patch window 26.16-26.18.

Top 10 High Elo Cassiopeia Mid all-role weakest synergies

  1. Renekton Top - High Elo data: Cassiopeia Mid vs Renekton Top, 45.0% observed win rate, -4.3 percentage points vs expected, 562 games, 3-patch window 26.16-26.18.
  2. Caitlyn ADC - High Elo data: Cassiopeia Mid vs Caitlyn ADC, 45.0% observed win rate, -3.6 percentage points vs expected, 1,092 games, 3-patch window 26.16-26.18.
  3. Lulu Support - High Elo data: Cassiopeia Mid vs Lulu Support, 47.0% observed win rate, -2.7 percentage points vs expected, 1,161 games, 3-patch window 26.16-26.18.
  4. Graves Jungle - High Elo data: Cassiopeia Mid vs Graves Jungle, 46.8% observed win rate, -2.7 percentage points vs expected, 1,128 games, 3-patch window 26.16-26.18.
  5. Malphite Top - High Elo data: Cassiopeia Mid vs Malphite Top, 48.0% observed win rate, -2.6 percentage points vs expected, 506 games, 3-patch window 26.16-26.18.
  6. Darius Top - High Elo data: Cassiopeia Mid vs Darius Top, 47.2% observed win rate, -2.5 percentage points vs expected, 532 games, 3-patch window 26.16-26.18.
  7. Seraphine Support - High Elo data: Cassiopeia Mid vs Seraphine Support, 48.1% observed win rate, -2.0 percentage points vs expected, 651 games, 3-patch window 26.16-26.18.
  8. Sylas Jungle - High Elo data: Cassiopeia Mid vs Sylas Jungle, 48.6% observed win rate, -1.9 percentage points vs expected, 504 games, 3-patch window 26.16-26.18.
  9. Janna Support - High Elo data: Cassiopeia Mid vs Janna Support, 49.2% observed win rate, -1.7 percentage points vs expected, 504 games, 3-patch window 26.16-26.18.
  10. Jinx ADC - High Elo data: Cassiopeia Mid vs Jinx ADC, 49.9% observed win rate, -1.7 percentage points vs expected, 1,175 games, 3-patch window 26.16-26.18.