Ezreal ADC vs Pantheon Support Matchup
Ezreal ADC wins 48.4% of 4,268 Low Elo games against Pantheon Support, +0.5 points vs expected, 2-patch window 26.19-26.20.
Researched on LoL patch 26.20. Tips are written to hold at any rank; stats come from Low Elo ranked games up to patch 26.20.
Why Ezreal is favored
Pantheon must get close to land his point-targeted stun, while Ezreal can pressure him from outside that range with Q and reposition with E. That range advantage gives Ezreal more chances to chip Pantheon down before he can start an all-in.
Measured in High Elo: Ezreal wins 1.4pp more often than expected over 1,219 games.
How to play as Ezreal
Stay outside Pantheon's W range and use Q to chip him when you have a clear shot; don't step forward just to trade autos before he has spent his engage.
Let the wave come toward your side and farm safely through Pantheon's early all-in window; if he commits W without a follow-up kill, use the breathing room to poke and push the lane back.
Pantheon's W is a 600-range dash and stun, while Ezreal's Q reaches 1,150, letting Ezreal threaten him from farther away.
Sources
These notes come from r/supportlol and r/summonerschool, checked against the champions' abilities.