Kai'Sa vs Ezreal ADC Matchup

Kai'Sa ADC wins 55.5% of 19,083 Low Elo games against Ezreal ADC, +1.7 points vs expected, 2-patch window 26.19-26.20.

Researched on LoL patch 26.20. Tips are written to hold at any rank; stats come from Low Elo ranked games up to patch 26.20.

How to play as Kai'Sa

Push the wave with Icathian Rain(Q) to maintain minion cover; staying behind friendly minions completely blocks Ezreal's Mystic Shot(Q) poke while pinning him under tower.

Use Killer Instinct(R) only while Ezreal remains visible and Plasma-marked and is within your current rank's range; if he spends Arcane Shift(E), choose a safe landing angle and follow with Q only when he is isolated.

Icathian Rain(Q) concentrates its full damage onto a single enemy when no other minions or targets are nearby, dealing massive isolated burst.

Killer Instinct(R) can dash only to a visible enemy champion marked with Plasma, and its range grows with Kai'Sa's rank; Arcane Shift(E) can reposition Ezreal before the dash begins.

Both Mystic Shot(Q) and Void Seeker(W) are single-target skillshots stopped by minion collision, making neutral trades heavily reliant on minion cover.

How to play as Ezreal

Trade only while standing inside your own minion wave; minions scatter Kai'Sa's Icathian Rain(Q) missiles and block Void Seeker(W), denying her isolated burst.

Never use Arcane Shift(E) aggressively forward into Kai'Sa; blowing your blink leaves you stranded in close range where Kai'Sa's ramping attack speed and Second Skin(P) Plasma procs out-duel you.

Sources

These notes come from r/kaisamains and LoL Wiki, checked against the champions' abilities.