Best Lissandra Synergies

The best partner with Lissandra is Lucian ADC. The pair wins 52.2% across 5,923 games, 1.3 points more than the two champions' own win rates predict. Rengar Jungle (+1.3 over 2,582 games) and Master Yi Jungle (+1.2 over 7,499 games) also over-perform. Based on Low Elo Ranked Solo/Duo games, patches 26.20-26.22. These are observed associations, not guaranteed outcomes. The weakest listed synergies for Lissandra are FiddleSticks Jungle, Zac Jungle, Lillia Jungle, Nidalee Jungle, Teemo Top, Amumu Jungle, Sejuani Jungle, Cho'Gath Jungle, Heimerdinger Top, and Ekko Jungle. The detailed info below lists each partner with observed win rate, expected win rate delta, sample size, rank scope, and patch window.

Updated 2026-11-15. Data is current for LoL patch 26.22 (all regions, low elo and high elo).

Top 10 Low Elo Lissandra strongest synergies

  1. Lucian ADC - 52.2% win rate with Lissandra Mid (+1.3 points vs expected), 5,923 games.
  2. Rengar Jungle - 46.9% win rate with Lissandra Mid (+1.3 points vs expected), 2,582 games.
  3. Master Yi Jungle - 53.2% win rate with Lissandra Mid (+1.2 points vs expected), 7,499 games.
  4. Naafiri Jungle - 52.2% win rate with Lissandra Mid (+1.2 points vs expected), 2,498 games.
  5. Kha'Zix Jungle - 51.2% win rate with Lissandra Mid (+1.2 points vs expected), 4,604 games.
  6. Viego Jungle - 52.9% win rate with Lissandra Mid (+1.1 points vs expected), 7,179 games.
  7. Graves Jungle - 52.1% win rate with Lissandra Mid (+1.0 points vs expected), 6,080 games.
  8. Zed Jungle - 49.4% win rate with Lissandra Mid (+1.0 points vs expected), 2,158 games.
  9. Talon Jungle - 50.8% win rate with Lissandra Mid (+0.9 points vs expected), 3,250 games.
  10. Nocturne Jungle - 51.5% win rate with Lissandra Mid (+0.9 points vs expected), 4,708 games.

Top 10 Low Elo Lissandra weakest synergies

  1. FiddleSticks Jungle - 49.1% win rate with Lissandra Mid (-1.9 points vs expected), 1,283 games.
  2. Zac Jungle - 52.8% win rate with Lissandra Mid (-1.2 points vs expected), 1,435 games.
  3. Lillia Jungle - 51.6% win rate with Lissandra Mid (-1.1 points vs expected), 3,364 games.
  4. Nidalee Jungle - 47.2% win rate with Lissandra Mid (-1.0 points vs expected), 1,230 games.
  5. Teemo Top - 51.0% win rate with Lissandra Mid (-0.9 points vs expected), 4,634 games.
  6. Amumu Jungle - 52.7% win rate with Lissandra Mid (-0.8 points vs expected), 2,479 games.
  7. Sejuani Jungle - 50.6% win rate with Lissandra Mid (-0.8 points vs expected), 1,720 games.
  8. Cho'Gath Jungle - 52.7% win rate with Lissandra Mid (-0.7 points vs expected), 4,993 games.
  9. Heimerdinger Top - 50.0% win rate with Lissandra Mid (-0.7 points vs expected), 1,250 games.
  10. Ekko Jungle - 51.2% win rate with Lissandra Mid (-0.7 points vs expected), 2,473 games.

Top 10 High Elo Lissandra strongest synergies

  1. Viego Jungle - 52.2% win rate with Lissandra Mid (+1.3 points vs expected), 6,618 games.
  2. Samira ADC - 52.0% win rate with Lissandra Mid (+1.0 points vs expected), 2,341 games.
  3. Rengar Jungle - 50.1% win rate with Lissandra Mid (+0.9 points vs expected), 3,146 games.
  4. Yone Mid - 53.8% win rate with Lissandra Top (+0.9 points vs expected), 1,036 games.
  5. Kai'Sa ADC - 52.3% win rate with Lissandra Mid (+0.9 points vs expected), 15,594 games.
  6. Draven ADC - 53.0% win rate with Lissandra Mid (+0.9 points vs expected), 2,968 games.
  7. Kha'Zix Jungle - 52.0% win rate with Lissandra Mid (+0.8 points vs expected), 5,396 games.
  8. Graves Jungle - 52.5% win rate with Lissandra Mid (+0.8 points vs expected), 6,999 games.
  9. Master Yi Jungle - 53.2% win rate with Lissandra Mid (+0.7 points vs expected), 4,028 games.
  10. Kayn Jungle - 51.0% win rate with Lissandra Mid (+0.7 points vs expected), 4,247 games.

Top 10 High Elo Lissandra weakest synergies

  1. Taliyah Jungle - 51.5% win rate with Lissandra Mid (-1.3 points vs expected), 1,255 games.
  2. Viktor ADC - 49.5% win rate with Lissandra Mid (-1.1 points vs expected), 1,042 games.
  3. Ashe ADC - 47.7% win rate with Lissandra Mid (-1.0 points vs expected), 3,268 games.
  4. Smolder ADC - 47.8% win rate with Lissandra Mid (-0.9 points vs expected), 2,601 games.
  5. Zac Jungle - 49.9% win rate with Lissandra Mid (-0.9 points vs expected), 1,562 games.
  6. Varus ADC - 49.3% win rate with Lissandra Mid (-0.8 points vs expected), 2,172 games.
  7. Lillia Jungle - 51.0% win rate with Lissandra Mid (-0.7 points vs expected), 2,199 games.
  8. Elise Jungle - 51.9% win rate with Lissandra Mid (-0.6 points vs expected), 1,722 games.
  9. Kog'Maw ADC - 53.4% win rate with Lissandra Mid (-0.6 points vs expected), 1,509 games.
  10. Sejuani Jungle - 51.2% win rate with Lissandra Mid (-0.6 points vs expected), 1,045 games.

How these matchup statistics are calculated

Counter and synergy statistics use Ranked Solo/Duo games, exclude matches shorter than 600 seconds, and group results by patch window, region, rank scope, and champion role.

Pairwise pages use a rolling three-patch window and compare observed win rate with a log-odds expected win rate based on each champion's role-adjusted baseline; listed pairs require at least 1,000 games.

Read the full methodology for the model and guidance on interpreting these results.