Best Pantheon Mid Synergies

The best partner with Pantheon Mid is Mordekaiser Top. The pair wins 55.8% across 2,421 games, 0.8 points more than the two champions' own win rates predict. Lillia Jungle (+0.7 over 1,730 games) and Teemo Top (+0.7 over 1,646 games) also over-perform. Based on Low Elo Ranked Solo/Duo games, patches 26.20-26.22. These are observed associations, not guaranteed outcomes. The weakest listed synergies for Pantheon Mid are Master Yi Jungle, Graves Jungle, Viego Jungle, Yone Top, Blitzcrank Support, Nautilus Support, Pyke Support, Tristana ADC, Briar Jungle, and Darius Top. The detailed info below lists each partner with observed win rate, expected win rate delta, sample size, rank scope, and patch window.

Updated 2026-11-15. Data is current for LoL patch 26.22 (all regions, low elo and high elo).

Top 10 Low Elo Pantheon Mid all-role strongest synergies

  1. Mordekaiser Top - 55.8% win rate with Pantheon Mid (+0.8 points vs expected), 2,421 games.
  2. Lillia Jungle - 55.8% win rate with Pantheon Mid (+0.7 points vs expected), 1,730 games.
  3. Teemo Top - 51.8% win rate with Pantheon Mid (+0.7 points vs expected), 1,646 games.
  4. Seraphine Support - 55.3% win rate with Pantheon Mid (+0.7 points vs expected), 2,045 games.
  5. Senna Support - 54.2% win rate with Pantheon Mid (+0.6 points vs expected), 1,048 games.
  6. Cho'Gath Jungle - 54.5% win rate with Pantheon Mid (+0.5 points vs expected), 1,444 games.
  7. Lux Support - 50.9% win rate with Pantheon Mid (+0.5 points vs expected), 2,974 games.
  8. Ekko Jungle - 52.3% win rate with Pantheon Mid (+0.5 points vs expected), 1,158 games.
  9. Malphite Top - 53.4% win rate with Pantheon Mid (+0.5 points vs expected), 1,512 games.
  10. Lulu Support - 51.6% win rate with Pantheon Mid (+0.4 points vs expected), 1,669 games.

Top 10 Low Elo Pantheon Mid all-role weakest synergies

  1. Master Yi Jungle - 52.0% win rate with Pantheon Mid (-0.7 points vs expected), 1,638 games.
  2. Graves Jungle - 47.6% win rate with Pantheon Mid (-0.6 points vs expected), 1,004 games.
  3. Viego Jungle - 50.3% win rate with Pantheon Mid (-0.6 points vs expected), 1,530 games.
  4. Yone Top - 50.5% win rate with Pantheon Mid (-0.6 points vs expected), 1,570 games.
  5. Blitzcrank Support - 48.8% win rate with Pantheon Mid (-0.6 points vs expected), 1,362 games.
  6. Nautilus Support - 49.6% win rate with Pantheon Mid (-0.5 points vs expected), 2,131 games.
  7. Pyke Support - 50.1% win rate with Pantheon Mid (-0.5 points vs expected), 1,056 games.
  8. Tristana ADC - 47.3% win rate with Pantheon Mid (-0.5 points vs expected), 1,594 games.
  9. Briar Jungle - 53.7% win rate with Pantheon Mid (-0.5 points vs expected), 1,018 games.
  10. Darius Top - 50.1% win rate with Pantheon Mid (-0.4 points vs expected), 1,511 games.

Top 9 High Elo Pantheon Mid all-role strongest synergies

  1. Taliyah Jungle - 55.9% win rate with Pantheon Mid (+0.8 points vs expected), 1,037 games.
  2. Kai'Sa ADC - 54.2% win rate with Pantheon Mid (+0.8 points vs expected), 2,581 games.
  3. Lulu Support - 50.5% win rate with Pantheon Mid (+0.3 points vs expected), 1,447 games.
  4. Nidalee Jungle - 54.8% win rate with Pantheon Mid (+0.2 points vs expected), 1,286 games.
  5. Jhin ADC - 51.2% win rate with Pantheon Mid (+0.2 points vs expected), 2,127 games.
  6. Yunara ADC - 52.8% win rate with Pantheon Mid (+0.2 points vs expected), 1,138 games.
  7. Caitlyn ADC - 49.3% win rate with Pantheon Mid (+0.1 points vs expected), 1,166 games.
  8. Sylas Jungle - 52.5% win rate with Pantheon Mid (+0.0 points vs expected), 1,368 games.
  9. Jinx ADC - 53.1% win rate with Pantheon Mid (+0.0 points vs expected), 1,209 games.

Top 4 High Elo Pantheon Mid all-role weakest synergies

  1. Lee Sin Jungle - 50.9% win rate with Pantheon Mid (-0.3 points vs expected), 1,211 games.
  2. Nautilus Support - 50.1% win rate with Pantheon Mid (-0.3 points vs expected), 1,398 games.
  3. Thresh Support - 52.0% win rate with Pantheon Mid (-0.2 points vs expected), 1,556 games.
  4. Ezreal ADC - 45.6% win rate with Pantheon Mid (-0.1 points vs expected), 1,374 games.

How these matchup statistics are calculated

Counter and synergy statistics use Ranked Solo/Duo games, exclude matches shorter than 600 seconds, and group results by patch window, region, rank scope, and champion role.

Pairwise pages use a rolling three-patch window and compare observed win rate with a log-odds expected win rate based on each champion's role-adjusted baseline; listed pairs require at least 1,000 games.

Read the full methodology for the model and guidance on interpreting these results.