Best Seraphine Synergies

Use RiftMind to compare Seraphine synergies, weak synergy partners, duo win rates, synergy deltas, sample sizes, and role-specific partner picks for low and high Elo League of Legends team comps.

Updated 2026-09-20. Data is current for LoL patch 26.18 (all regions, low elo and high elo).

How these matchup statistics are calculated

Counter and synergy statistics use Ranked Solo/Duo games, exclude matches shorter than 600 seconds, and group results by patch window, region, rank scope, and champion role.

Pairwise pages use a rolling three-patch window and compare observed win rate with a log-odds expected win rate based on each champion's role-adjusted baseline; listed pairs require at least 500 games.

Read the full methodology for the model and guidance on interpreting these results.

Summary

Low Elo data lists Master Yi Jungle, Heimerdinger Mid, Dr. Mundo Jungle, Nilah ADC, Bel'Veth Jungle, Nautilus Support, Zed Mid, Gangplank Mid, Tryndamere Top, and Viego Jungle as the strongest synergy partners for Seraphine. The weakest listed synergies for Seraphine are Syndra Mid, Shaco Jungle, Ziggs ADC, Mordekaiser Top, Jarvan IV Jungle, Swain Mid, Pantheon Jungle, Teemo Top, Malphite Top, and Hwei ADC. The detailed info below lists each partner with observed win rate, expected win rate delta, sample size, rank scope, and patch window.

Detailed info:

Top 10 Low Elo Seraphine strongest synergies

  1. Master Yi Jungle - Low Elo data: Seraphine ADC vs Master Yi Jungle, 58.5% observed win rate, +5.4 percentage points vs expected, 997 games, 3-patch window 26.16-26.18.
  2. Heimerdinger Mid - Low Elo data: Seraphine Support vs Heimerdinger Mid, 59.7% observed win rate, +5.0 percentage points vs expected, 528 games, 3-patch window 26.16-26.18.
  3. Dr. Mundo Jungle - Low Elo data: Seraphine Support vs Dr. Mundo Jungle, 57.6% observed win rate, +4.7 percentage points vs expected, 637 games, 3-patch window 26.16-26.18.
  4. Nilah ADC - Low Elo data: Seraphine Support vs Nilah ADC, 58.1% observed win rate, +4.3 percentage points vs expected, 959 games, 3-patch window 26.16-26.18.
  5. Bel'Veth Jungle - Low Elo data: Seraphine ADC vs Bel'Veth Jungle, 59.2% observed win rate, +4.2 percentage points vs expected, 510 games, 3-patch window 26.16-26.18.
  6. Nautilus Support - Low Elo data: Seraphine ADC vs Nautilus Support, 57.3% observed win rate, +4.1 percentage points vs expected, 934 games, 3-patch window 26.16-26.18.
  7. Zed Mid - Low Elo data: Seraphine ADC vs Zed Mid, 56.7% observed win rate, +4.1 percentage points vs expected, 1,438 games, 3-patch window 26.16-26.18.
  8. Gangplank Mid - Low Elo data: Seraphine Support vs Gangplank Mid, 55.2% observed win rate, +4.0 percentage points vs expected, 569 games, 3-patch window 26.16-26.18.
  9. Tryndamere Top - Low Elo data: Seraphine ADC vs Tryndamere Top, 58.1% observed win rate, +4.0 percentage points vs expected, 503 games, 3-patch window 26.16-26.18.
  10. Viego Jungle - Low Elo data: Seraphine ADC vs Viego Jungle, 57.0% observed win rate, +3.9 percentage points vs expected, 1,333 games, 3-patch window 26.16-26.18.

Top 10 Low Elo Seraphine weakest synergies

  1. Syndra Mid - Low Elo data: Seraphine ADC vs Syndra Mid, 48.0% observed win rate, -5.8 percentage points vs expected, 631 games, 3-patch window 26.16-26.18.
  2. Shaco Jungle - Low Elo data: Seraphine ADC vs Shaco Jungle, 48.9% observed win rate, -4.2 percentage points vs expected, 626 games, 3-patch window 26.16-26.18.
  3. Ziggs ADC - Low Elo data: Seraphine Support vs Ziggs ADC, 49.2% observed win rate, -3.9 percentage points vs expected, 2,166 games, 3-patch window 26.16-26.18.
  4. Mordekaiser Top - Low Elo data: Seraphine ADC vs Mordekaiser Top, 50.8% observed win rate, -3.7 percentage points vs expected, 730 games, 3-patch window 26.16-26.18.
  5. Jarvan IV Jungle - Low Elo data: Seraphine ADC vs Jarvan IV Jungle, 50.4% observed win rate, -3.6 percentage points vs expected, 534 games, 3-patch window 26.16-26.18.
  6. Swain Mid - Low Elo data: Seraphine Support vs Swain Mid, 49.7% observed win rate, -3.5 percentage points vs expected, 593 games, 3-patch window 26.16-26.18.
  7. Pantheon Jungle - Low Elo data: Seraphine Support vs Pantheon Jungle, 46.3% observed win rate, -3.4 percentage points vs expected, 902 games, 3-patch window 26.16-26.18.
  8. Teemo Top - Low Elo data: Seraphine ADC vs Teemo Top, 52.5% observed win rate, -3.0 percentage points vs expected, 690 games, 3-patch window 26.16-26.18.
  9. Malphite Top - Low Elo data: Seraphine ADC vs Malphite Top, 52.2% observed win rate, -3.0 percentage points vs expected, 768 games, 3-patch window 26.16-26.18.
  10. Hwei ADC - Low Elo data: Seraphine Support vs Hwei ADC, 51.1% observed win rate, -3.0 percentage points vs expected, 931 games, 3-patch window 26.16-26.18.

Top 10 High Elo Seraphine strongest synergies

  1. Karma Support - High Elo data: Seraphine ADC vs Karma Support, 55.2% observed win rate, +4.6 percentage points vs expected, 930 games, 3-patch window 26.16-26.18.
  2. Rengar Jungle - High Elo data: Seraphine ADC vs Rengar Jungle, 55.7% observed win rate, +4.6 percentage points vs expected, 623 games, 3-patch window 26.16-26.18.
  3. Master Yi Jungle - High Elo data: Seraphine ADC vs Master Yi Jungle, 56.0% observed win rate, +4.3 percentage points vs expected, 678 games, 3-patch window 26.16-26.18.
  4. Darius Top - High Elo data: Seraphine ADC vs Darius Top, 55.9% observed win rate, +4.3 percentage points vs expected, 810 games, 3-patch window 26.16-26.18.
  5. Pantheon Top - High Elo data: Seraphine Support vs Pantheon Top, 54.8% observed win rate, +3.7 percentage points vs expected, 1,171 games, 3-patch window 26.16-26.18.
  6. Vi Jungle - High Elo data: Seraphine Support vs Vi Jungle, 53.1% observed win rate, +3.7 percentage points vs expected, 1,690 games, 3-patch window 26.16-26.18.
  7. Bel'Veth Jungle - High Elo data: Seraphine ADC vs Bel'Veth Jungle, 55.0% observed win rate, +3.6 percentage points vs expected, 531 games, 3-patch window 26.16-26.18.
  8. Dr. Mundo Top - High Elo data: Seraphine Support vs Dr. Mundo Top, 53.1% observed win rate, +3.3 percentage points vs expected, 1,466 games, 3-patch window 26.16-26.18.
  9. Warwick Jungle - High Elo data: Seraphine Support vs Warwick Jungle, 54.1% observed win rate, +3.2 percentage points vs expected, 857 games, 3-patch window 26.16-26.18.
  10. Ryze Mid - High Elo data: Seraphine Support vs Ryze Mid, 50.6% observed win rate, +3.1 percentage points vs expected, 1,252 games, 3-patch window 26.16-26.18.

Top 10 High Elo Seraphine weakest synergies

  1. Mel ADC - High Elo data: Seraphine Support vs Mel ADC, 41.5% observed win rate, -5.2 percentage points vs expected, 858 games, 3-patch window 26.16-26.18.
  2. Lux Support - High Elo data: Seraphine ADC vs Lux Support, 45.4% observed win rate, -4.9 percentage points vs expected, 895 games, 3-patch window 26.16-26.18.
  3. Syndra Mid - High Elo data: Seraphine ADC vs Syndra Mid, 48.5% observed win rate, -3.5 percentage points vs expected, 752 games, 3-patch window 26.16-26.18.
  4. Hwei ADC - High Elo data: Seraphine Support vs Hwei ADC, 49.9% observed win rate, -3.5 percentage points vs expected, 814 games, 3-patch window 26.16-26.18.
  5. Akali Mid - High Elo data: Seraphine ADC vs Akali Mid, 47.6% observed win rate, -3.4 percentage points vs expected, 561 games, 3-patch window 26.16-26.18.
  6. Aurelion Sol Mid - High Elo data: Seraphine Support vs Aurelion Sol Mid, 47.6% observed win rate, -3.3 percentage points vs expected, 643 games, 3-patch window 26.16-26.18.
  7. Senna ADC - High Elo data: Seraphine Support vs Senna ADC, 48.3% observed win rate, -2.9 percentage points vs expected, 534 games, 3-patch window 26.16-26.18.
  8. Diana Mid - High Elo data: Seraphine Support vs Diana Mid, 48.0% observed win rate, -2.9 percentage points vs expected, 1,092 games, 3-patch window 26.16-26.18.
  9. Gragas Top - High Elo data: Seraphine Support vs Gragas Top, 48.5% observed win rate, -2.5 percentage points vs expected, 987 games, 3-patch window 26.16-26.18.
  10. Malphite Top - High Elo data: Seraphine Support vs Malphite Top, 49.0% observed win rate, -2.4 percentage points vs expected, 2,557 games, 3-patch window 26.16-26.18.