Kai'Sa vs Yasuo ADC Matchup
Kai'Sa ADC wins 48.8% of 2,936 Low Elo games against Yasuo ADC, +0.6 points vs expected, 2-patch window 26.19-26.20.
Researched on LoL patch 26.20. Tips are written to hold at any rank; stats come from Low Elo ranked games up to patch 26.20.
How to play as Kai'Sa
Use your range to pressure Yasuo early, then stop chasing trades once he can chain Sweeping Blade(E) through the wave; freezing near your tower makes his all-in harder to set up.
Track Wind Wall(W) before firing Q or W. Wait out the wall or change your angle, since his projectile block lasts four seconds and has a long cooldown.
Wind Wall(W) blocks Kai'Sa's Icathian Rain(Q) and Void Seeker(W) projectiles, so Yasuo can deny both her burst missiles and her long-range Plasma mark for four seconds.
How to play as Yasuo
Sweeping Blade(E) can chain through fresh minions to close distance, so standing in the wave gives Yasuo more routes to reach Kai'Sa.
Sources
These notes come from r/ADCMains, checked against the champions' abilities.