Best Seraphine Support Synergies

Compare Seraphine Support strongest and weakest synergies by duo win rate, expected win rate, delta, sample size, and allied role for team comp planning.

Updated 2026-09-20. Data is current for LoL patch 26.18 (all regions, low elo and high elo).

How these matchup statistics are calculated

Counter and synergy statistics use Ranked Solo/Duo games, exclude matches shorter than 600 seconds, and group results by patch window, region, rank scope, and champion role.

Pairwise pages use a rolling three-patch window and compare observed win rate with a log-odds expected win rate based on each champion's role-adjusted baseline; listed pairs require at least 500 games.

Read the full methodology for the model and guidance on interpreting these results.

Summary

Low Elo data lists Nilah ADC, Ashe ADC, Vayne ADC, Kai'Sa ADC, Yasuo ADC, Brand ADC, Corki ADC, Kalista ADC, Swain ADC, and Twitch ADC as the strongest ADC duo partners for Seraphine Support. The weakest listed synergies for Seraphine Support are Ziggs ADC, Hwei ADC, Viktor ADC, Syndra ADC, Xerath ADC, Smolder ADC, Zeri ADC, Sivir ADC, Jinx ADC, and Lux ADC. The detailed info below lists each partner with observed win rate, expected win rate delta, sample size, rank scope, and patch window.

Detailed info:

Top 10 Low Elo Seraphine Support bot-lane duo synergies with ADC

  1. Nilah ADC - Low Elo data: Seraphine Support vs Nilah ADC, 58.1% observed win rate, +4.3 percentage points vs expected, 959 games, 3-patch window 26.16-26.18.
  2. Ashe ADC - Low Elo data: Seraphine Support vs Ashe ADC, 53.4% observed win rate, +2.4 percentage points vs expected, 22,203 games, 3-patch window 26.16-26.18.
  3. Vayne ADC - Low Elo data: Seraphine Support vs Vayne ADC, 51.7% observed win rate, +1.6 percentage points vs expected, 4,061 games, 3-patch window 26.16-26.18.
  4. Kai'Sa ADC - Low Elo data: Seraphine Support vs Kai'Sa ADC, 52.4% observed win rate, +1.4 percentage points vs expected, 11,638 games, 3-patch window 26.16-26.18.
  5. Yasuo ADC - Low Elo data: Seraphine Support vs Yasuo ADC, 53.6% observed win rate, +1.4 percentage points vs expected, 1,115 games, 3-patch window 26.16-26.18.
  6. Brand ADC - Low Elo data: Seraphine Support vs Brand ADC, 55.2% observed win rate, +1.3 percentage points vs expected, 600 games, 3-patch window 26.16-26.18.
  7. Corki ADC - Low Elo data: Seraphine Support vs Corki ADC, 51.2% observed win rate, +0.9 percentage points vs expected, 760 games, 3-patch window 26.16-26.18.
  8. Kalista ADC - Low Elo data: Seraphine Support vs Kalista ADC, 49.9% observed win rate, +0.8 percentage points vs expected, 871 games, 3-patch window 26.16-26.18.
  9. Swain ADC - Low Elo data: Seraphine Support vs Swain ADC, 55.6% observed win rate, +0.6 percentage points vs expected, 802 games, 3-patch window 26.16-26.18.
  10. Twitch ADC - Low Elo data: Seraphine Support vs Twitch ADC, 53.2% observed win rate, +0.4 percentage points vs expected, 4,380 games, 3-patch window 26.16-26.18.

Top 10 Low Elo Seraphine Support weakest bot-lane duo synergies with ADC

  1. Ziggs ADC - Low Elo data: Seraphine Support vs Ziggs ADC, 49.2% observed win rate, -3.9 percentage points vs expected, 2,166 games, 3-patch window 26.16-26.18.
  2. Hwei ADC - Low Elo data: Seraphine Support vs Hwei ADC, 51.1% observed win rate, -3.0 percentage points vs expected, 931 games, 3-patch window 26.16-26.18.
  3. Viktor ADC - Low Elo data: Seraphine Support vs Viktor ADC, 50.0% observed win rate, -2.7 percentage points vs expected, 1,965 games, 3-patch window 26.16-26.18.
  4. Syndra ADC - Low Elo data: Seraphine Support vs Syndra ADC, 47.9% observed win rate, -2.6 percentage points vs expected, 1,351 games, 3-patch window 26.16-26.18.
  5. Xerath ADC - Low Elo data: Seraphine Support vs Xerath ADC, 52.0% observed win rate, -1.8 percentage points vs expected, 1,166 games, 3-patch window 26.16-26.18.
  6. Smolder ADC - Low Elo data: Seraphine Support vs Smolder ADC, 51.0% observed win rate, -1.6 percentage points vs expected, 4,586 games, 3-patch window 26.16-26.18.
  7. Zeri ADC - Low Elo data: Seraphine Support vs Zeri ADC, 51.0% observed win rate, -1.5 percentage points vs expected, 1,982 games, 3-patch window 26.16-26.18.
  8. Sivir ADC - Low Elo data: Seraphine Support vs Sivir ADC, 50.5% observed win rate, -1.2 percentage points vs expected, 3,031 games, 3-patch window 26.16-26.18.
  9. Jinx ADC - Low Elo data: Seraphine Support vs Jinx ADC, 52.6% observed win rate, -1.1 percentage points vs expected, 13,463 games, 3-patch window 26.16-26.18.
  10. Lux ADC - Low Elo data: Seraphine Support vs Lux ADC, 53.8% observed win rate, -1.0 percentage points vs expected, 1,296 games, 3-patch window 26.16-26.18.

Top 10 Low Elo Seraphine Support all-role strongest synergies

  1. Heimerdinger Mid - Low Elo data: Seraphine Support vs Heimerdinger Mid, 59.7% observed win rate, +5.0 percentage points vs expected, 528 games, 3-patch window 26.16-26.18.
  2. Dr. Mundo Jungle - Low Elo data: Seraphine Support vs Dr. Mundo Jungle, 57.6% observed win rate, +4.7 percentage points vs expected, 637 games, 3-patch window 26.16-26.18.
  3. Nilah ADC - Low Elo data: Seraphine Support vs Nilah ADC, 58.1% observed win rate, +4.3 percentage points vs expected, 959 games, 3-patch window 26.16-26.18.
  4. Gangplank Mid - Low Elo data: Seraphine Support vs Gangplank Mid, 55.2% observed win rate, +4.0 percentage points vs expected, 569 games, 3-patch window 26.16-26.18.
  5. Vladimir Top - Low Elo data: Seraphine Support vs Vladimir Top, 53.5% observed win rate, +2.9 percentage points vs expected, 706 games, 3-patch window 26.16-26.18.
  6. Aatrox Top - Low Elo data: Seraphine Support vs Aatrox Top, 53.4% observed win rate, +2.5 percentage points vs expected, 4,375 games, 3-patch window 26.16-26.18.
  7. Ashe ADC - Low Elo data: Seraphine Support vs Ashe ADC, 53.4% observed win rate, +2.4 percentage points vs expected, 22,203 games, 3-patch window 26.16-26.18.
  8. Ambessa Jungle - Low Elo data: Seraphine Support vs Ambessa Jungle, 53.2% observed win rate, +2.4 percentage points vs expected, 502 games, 3-patch window 26.16-26.18.
  9. Garen Mid - Low Elo data: Seraphine Support vs Garen Mid, 56.8% observed win rate, +2.4 percentage points vs expected, 555 games, 3-patch window 26.16-26.18.
  10. Singed Top - Low Elo data: Seraphine Support vs Singed Top, 55.8% observed win rate, +2.3 percentage points vs expected, 1,768 games, 3-patch window 26.16-26.18.

Top 10 Low Elo Seraphine Support all-role weakest synergies

  1. Ziggs ADC - Low Elo data: Seraphine Support vs Ziggs ADC, 49.2% observed win rate, -3.9 percentage points vs expected, 2,166 games, 3-patch window 26.16-26.18.
  2. Swain Mid - Low Elo data: Seraphine Support vs Swain Mid, 49.7% observed win rate, -3.5 percentage points vs expected, 593 games, 3-patch window 26.16-26.18.
  3. Pantheon Jungle - Low Elo data: Seraphine Support vs Pantheon Jungle, 46.3% observed win rate, -3.4 percentage points vs expected, 902 games, 3-patch window 26.16-26.18.
  4. Hwei ADC - Low Elo data: Seraphine Support vs Hwei ADC, 51.1% observed win rate, -3.0 percentage points vs expected, 931 games, 3-patch window 26.16-26.18.
  5. Viktor ADC - Low Elo data: Seraphine Support vs Viktor ADC, 50.0% observed win rate, -2.7 percentage points vs expected, 1,965 games, 3-patch window 26.16-26.18.
  6. Syndra ADC - Low Elo data: Seraphine Support vs Syndra ADC, 47.9% observed win rate, -2.6 percentage points vs expected, 1,351 games, 3-patch window 26.16-26.18.
  7. Gwen Mid - Low Elo data: Seraphine Support vs Gwen Mid, 52.1% observed win rate, -2.4 percentage points vs expected, 956 games, 3-patch window 26.16-26.18.
  8. Quinn Top - Low Elo data: Seraphine Support vs Quinn Top, 48.4% observed win rate, -2.4 percentage points vs expected, 767 games, 3-patch window 26.16-26.18.
  9. Camille Top - Low Elo data: Seraphine Support vs Camille Top, 48.3% observed win rate, -2.2 percentage points vs expected, 2,209 games, 3-patch window 26.16-26.18.
  10. Kled Top - Low Elo data: Seraphine Support vs Kled Top, 49.9% observed win rate, -2.1 percentage points vs expected, 1,300 games, 3-patch window 26.16-26.18.

Top 10 High Elo Seraphine Support bot-lane duo synergies with ADC

  1. Zeri ADC - High Elo data: Seraphine Support vs Zeri ADC, 55.2% observed win rate, +2.6 percentage points vs expected, 1,415 games, 3-patch window 26.16-26.18.
  2. Ashe ADC - High Elo data: Seraphine Support vs Ashe ADC, 53.3% observed win rate, +2.2 percentage points vs expected, 12,983 games, 3-patch window 26.16-26.18.
  3. Vayne ADC - High Elo data: Seraphine Support vs Vayne ADC, 50.0% observed win rate, +1.5 percentage points vs expected, 1,126 games, 3-patch window 26.16-26.18.
  4. Syndra ADC - High Elo data: Seraphine Support vs Syndra ADC, 51.8% observed win rate, +0.7 percentage points vs expected, 1,518 games, 3-patch window 26.16-26.18.
  5. Yunara ADC - High Elo data: Seraphine Support vs Yunara ADC, 51.5% observed win rate, +0.6 percentage points vs expected, 2,787 games, 3-patch window 26.16-26.18.
  6. Veigar ADC - High Elo data: Seraphine Support vs Veigar ADC, 51.6% observed win rate, +0.5 percentage points vs expected, 803 games, 3-patch window 26.16-26.18.
  7. Ezreal ADC - High Elo data: Seraphine Support vs Ezreal ADC, 47.2% observed win rate, +0.5 percentage points vs expected, 5,476 games, 3-patch window 26.16-26.18.
  8. Viktor ADC - High Elo data: Seraphine Support vs Viktor ADC, 52.8% observed win rate, +0.5 percentage points vs expected, 1,802 games, 3-patch window 26.16-26.18.
  9. Jhin ADC - High Elo data: Seraphine Support vs Jhin ADC, 49.8% observed win rate, +0.3 percentage points vs expected, 6,019 games, 3-patch window 26.16-26.18.
  10. Tristana ADC - High Elo data: Seraphine Support vs Tristana ADC, 52.5% observed win rate, +0.2 percentage points vs expected, 2,425 games, 3-patch window 26.16-26.18.

Top 10 High Elo Seraphine Support weakest bot-lane duo synergies with ADC

  1. Mel ADC - High Elo data: Seraphine Support vs Mel ADC, 41.5% observed win rate, -5.2 percentage points vs expected, 858 games, 3-patch window 26.16-26.18.
  2. Hwei ADC - High Elo data: Seraphine Support vs Hwei ADC, 49.9% observed win rate, -3.5 percentage points vs expected, 814 games, 3-patch window 26.16-26.18.
  3. Senna ADC - High Elo data: Seraphine Support vs Senna ADC, 48.3% observed win rate, -2.9 percentage points vs expected, 534 games, 3-patch window 26.16-26.18.
  4. Corki ADC - High Elo data: Seraphine Support vs Corki ADC, 47.9% observed win rate, -2.2 percentage points vs expected, 607 games, 3-patch window 26.16-26.18.
  5. Ziggs ADC - High Elo data: Seraphine Support vs Ziggs ADC, 48.5% observed win rate, -2.1 percentage points vs expected, 1,016 games, 3-patch window 26.16-26.18.
  6. Kog'Maw ADC - High Elo data: Seraphine Support vs Kog'Maw ADC, 50.6% observed win rate, -1.9 percentage points vs expected, 512 games, 3-patch window 26.16-26.18.
  7. Draven ADC - High Elo data: Seraphine Support vs Draven ADC, 49.1% observed win rate, -1.8 percentage points vs expected, 900 games, 3-patch window 26.16-26.18.
  8. Varus ADC - High Elo data: Seraphine Support vs Varus ADC, 46.0% observed win rate, -1.8 percentage points vs expected, 973 games, 3-patch window 26.16-26.18.
  9. Lucian ADC - High Elo data: Seraphine Support vs Lucian ADC, 47.3% observed win rate, -1.8 percentage points vs expected, 1,542 games, 3-patch window 26.16-26.18.
  10. Smolder ADC - High Elo data: Seraphine Support vs Smolder ADC, 47.3% observed win rate, -1.6 percentage points vs expected, 1,387 games, 3-patch window 26.16-26.18.

Top 10 High Elo Seraphine Support all-role strongest synergies

  1. Pantheon Top - High Elo data: Seraphine Support vs Pantheon Top, 54.8% observed win rate, +3.7 percentage points vs expected, 1,171 games, 3-patch window 26.16-26.18.
  2. Vi Jungle - High Elo data: Seraphine Support vs Vi Jungle, 53.1% observed win rate, +3.7 percentage points vs expected, 1,690 games, 3-patch window 26.16-26.18.
  3. Dr. Mundo Top - High Elo data: Seraphine Support vs Dr. Mundo Top, 53.1% observed win rate, +3.3 percentage points vs expected, 1,466 games, 3-patch window 26.16-26.18.
  4. Warwick Jungle - High Elo data: Seraphine Support vs Warwick Jungle, 54.1% observed win rate, +3.2 percentage points vs expected, 857 games, 3-patch window 26.16-26.18.
  5. Ryze Mid - High Elo data: Seraphine Support vs Ryze Mid, 50.6% observed win rate, +3.1 percentage points vs expected, 1,252 games, 3-patch window 26.16-26.18.
  6. Irelia Mid - High Elo data: Seraphine Support vs Irelia Mid, 50.8% observed win rate, +2.7 percentage points vs expected, 1,066 games, 3-patch window 26.16-26.18.
  7. Cho'Gath Top - High Elo data: Seraphine Support vs Cho'Gath Top, 53.6% observed win rate, +2.6 percentage points vs expected, 1,134 games, 3-patch window 26.16-26.18.
  8. Zeri ADC - High Elo data: Seraphine Support vs Zeri ADC, 55.2% observed win rate, +2.6 percentage points vs expected, 1,415 games, 3-patch window 26.16-26.18.
  9. Sylas Mid - High Elo data: Seraphine Support vs Sylas Mid, 52.5% observed win rate, +2.5 percentage points vs expected, 2,751 games, 3-patch window 26.16-26.18.
  10. Azir Mid - High Elo data: Seraphine Support vs Azir Mid, 51.1% observed win rate, +2.5 percentage points vs expected, 691 games, 3-patch window 26.16-26.18.

Top 10 High Elo Seraphine Support all-role weakest synergies

  1. Mel ADC - High Elo data: Seraphine Support vs Mel ADC, 41.5% observed win rate, -5.2 percentage points vs expected, 858 games, 3-patch window 26.16-26.18.
  2. Hwei ADC - High Elo data: Seraphine Support vs Hwei ADC, 49.9% observed win rate, -3.5 percentage points vs expected, 814 games, 3-patch window 26.16-26.18.
  3. Aurelion Sol Mid - High Elo data: Seraphine Support vs Aurelion Sol Mid, 47.6% observed win rate, -3.3 percentage points vs expected, 643 games, 3-patch window 26.16-26.18.
  4. Senna ADC - High Elo data: Seraphine Support vs Senna ADC, 48.3% observed win rate, -2.9 percentage points vs expected, 534 games, 3-patch window 26.16-26.18.
  5. Diana Mid - High Elo data: Seraphine Support vs Diana Mid, 48.0% observed win rate, -2.9 percentage points vs expected, 1,092 games, 3-patch window 26.16-26.18.
  6. Gragas Top - High Elo data: Seraphine Support vs Gragas Top, 48.5% observed win rate, -2.5 percentage points vs expected, 987 games, 3-patch window 26.16-26.18.
  7. Malphite Top - High Elo data: Seraphine Support vs Malphite Top, 49.0% observed win rate, -2.4 percentage points vs expected, 2,557 games, 3-patch window 26.16-26.18.
  8. Talon Mid - High Elo data: Seraphine Support vs Talon Mid, 48.4% observed win rate, -2.3 percentage points vs expected, 748 games, 3-patch window 26.16-26.18.
  9. Gangplank Top - High Elo data: Seraphine Support vs Gangplank Top, 49.8% observed win rate, -2.3 percentage points vs expected, 2,120 games, 3-patch window 26.16-26.18.
  10. Karthus Jungle - High Elo data: Seraphine Support vs Karthus Jungle, 48.4% observed win rate, -2.3 percentage points vs expected, 517 games, 3-patch window 26.16-26.18.