Best Seraphine Support Synergies

The best ADC with Seraphine Support is Ashe. The pair wins 52.4% across 58,987 games, 1.7 points more than the two champions' own win rates predict. Yasuo (+1.2 over 2,090 games) and Vayne (+1.1 over 6,639 games) also over-perform. Based on Low Elo Ranked Solo/Duo games, patches 26.20-26.22. These are observed associations, not guaranteed outcomes. The weakest listed synergies for Seraphine Support are Ziggs ADC, Samira ADC, Lucian ADC, Hwei ADC, Swain ADC, Yunara ADC, Jinx ADC, Mel ADC, Aphelios ADC, and Xayah ADC. The detailed info below lists each partner with observed win rate, expected win rate delta, sample size, rank scope, and patch window.

Updated 2026-11-15. Data is current for LoL patch 26.22 (all regions, low elo and high elo).

Seraphine Support duo tips

  1. Ashe & Seraphine - Ashe's repeated slows make Seraphine's Beat Drop(E) a root, and its echoed hit can stun a target already rooted. Ashe can also follow Seraphine's Encore(R) with her own arrow, giving the duo a reliable long-range chain of crowd control and poke.
  2. Nilah & Seraphine - Nilah's passive enhances nearby healing and shielding; Seraphine W shields nearby allies and can also heal them when she is already shielded.

Top 7 Low Elo Seraphine Support bot-lane duo synergies with ADC

  1. Ashe ADC - 52.4% win rate with Seraphine Support (+1.7 points vs expected), 58,987 games.
  2. Yasuo ADC - 55.6% win rate with Seraphine Support (+1.2 points vs expected), 2,090 games.
  3. Vayne ADC - 51.8% win rate with Seraphine Support (+1.1 points vs expected), 6,639 games.
  4. Ezreal ADC - 48.6% win rate with Seraphine Support (+0.8 points vs expected), 21,423 games.
  5. Draven ADC - 51.0% win rate with Seraphine Support (+0.6 points vs expected), 3,845 games.
  6. Nilah ADC - 55.1% win rate with Seraphine Support (+0.4 points vs expected), 1,637 games.
  7. Kai'Sa ADC - 51.3% win rate with Seraphine Support (+0.2 points vs expected), 24,523 games.

Top 10 Low Elo Seraphine Support weakest bot-lane duo synergies with ADC

  1. Ziggs ADC - 50.0% win rate with Seraphine Support (-1.9 points vs expected), 3,113 games.
  2. Samira ADC - 49.7% win rate with Seraphine Support (-1.4 points vs expected), 4,697 games.
  3. Lucian ADC - 47.8% win rate with Seraphine Support (-1.3 points vs expected), 6,680 games.
  4. Hwei ADC - 52.0% win rate with Seraphine Support (-0.9 points vs expected), 1,230 games.
  5. Swain ADC - 54.4% win rate with Seraphine Support (-0.7 points vs expected), 1,698 games.
  6. Yunara ADC - 49.6% win rate with Seraphine Support (-0.7 points vs expected), 12,262 games.
  7. Jinx ADC - 51.8% win rate with Seraphine Support (-0.7 points vs expected), 21,363 games.
  8. Mel ADC - 48.6% win rate with Seraphine Support (-0.7 points vs expected), 1,977 games.
  9. Aphelios ADC - 50.1% win rate with Seraphine Support (-0.7 points vs expected), 9,184 games.
  10. Xayah ADC - 52.1% win rate with Seraphine Support (-0.7 points vs expected), 7,869 games.

Top 10 Low Elo Seraphine Support all-role strongest synergies

  1. Ashe ADC - 52.4% win rate with Seraphine Support (+1.7 points vs expected), 58,987 games.
  2. Yasuo ADC - 55.6% win rate with Seraphine Support (+1.2 points vs expected), 2,090 games.
  3. Warwick Jungle - 54.8% win rate with Seraphine Support (+1.1 points vs expected), 10,903 games.
  4. Vayne ADC - 51.8% win rate with Seraphine Support (+1.1 points vs expected), 6,639 games.
  5. Maokai Jungle - 56.4% win rate with Seraphine Support (+0.9 points vs expected), 1,074 games.
  6. Irelia Mid - 53.0% win rate with Seraphine Support (+0.9 points vs expected), 5,347 games.
  7. Ezreal ADC - 48.6% win rate with Seraphine Support (+0.8 points vs expected), 21,423 games.
  8. Rammus Jungle - 53.7% win rate with Seraphine Support (+0.8 points vs expected), 4,958 games.
  9. Sejuani Jungle - 54.3% win rate with Seraphine Support (+0.7 points vs expected), 4,728 games.
  10. Tryndamere Jungle - 54.6% win rate with Seraphine Support (+0.7 points vs expected), 1,428 games.

Top 10 Low Elo Seraphine Support all-role weakest synergies

  1. Ziggs ADC - 50.0% win rate with Seraphine Support (-1.9 points vs expected), 3,113 games.
  2. FiddleSticks Jungle - 50.0% win rate with Seraphine Support (-1.4 points vs expected), 3,213 games.
  3. Taliyah Jungle - 48.3% win rate with Seraphine Support (-1.4 points vs expected), 1,433 games.
  4. Samira ADC - 49.7% win rate with Seraphine Support (-1.4 points vs expected), 4,697 games.
  5. Gangplank Top - 49.6% win rate with Seraphine Support (-1.4 points vs expected), 7,165 games.
  6. Lucian ADC - 47.8% win rate with Seraphine Support (-1.3 points vs expected), 6,680 games.
  7. Zyra Jungle - 52.4% win rate with Seraphine Support (-1.2 points vs expected), 2,380 games.
  8. Hwei Mid - 50.3% win rate with Seraphine Support (-1.2 points vs expected), 6,071 games.
  9. Lillia Jungle - 52.9% win rate with Seraphine Support (-1.1 points vs expected), 9,446 games.
  10. Xerath Mid - 51.1% win rate with Seraphine Support (-1.1 points vs expected), 6,127 games.

Top 8 High Elo Seraphine Support bot-lane duo synergies with ADC

  1. Vayne ADC - 52.1% win rate with Seraphine Support (+2.2 points vs expected), 1,669 games.
  2. Ashe ADC - 52.0% win rate with Seraphine Support (+2.1 points vs expected), 30,855 games.
  3. Tristana ADC - 51.9% win rate with Seraphine Support (+1.2 points vs expected), 3,325 games.
  4. Ezreal ADC - 47.6% win rate with Seraphine Support (+0.9 points vs expected), 10,636 games.
  5. Kog'Maw ADC - 52.4% win rate with Seraphine Support (+0.3 points vs expected), 1,222 games.
  6. Smolder ADC - 49.7% win rate with Seraphine Support (+0.3 points vs expected), 3,125 games.
  7. Draven ADC - 50.7% win rate with Seraphine Support (+0.2 points vs expected), 1,557 games.
  8. Kai'Sa ADC - 50.4% win rate with Seraphine Support (+0.1 points vs expected), 10,504 games.

Top 10 High Elo Seraphine Support weakest bot-lane duo synergies with ADC

  1. Samira ADC - 48.4% win rate with Seraphine Support (-1.7 points vs expected), 1,021 games.
  2. Lux ADC - 47.9% win rate with Seraphine Support (-1.6 points vs expected), 1,440 games.
  3. Miss Fortune ADC - 48.5% win rate with Seraphine Support (-1.5 points vs expected), 6,536 games.
  4. Ziggs ADC - 47.8% win rate with Seraphine Support (-1.4 points vs expected), 1,135 games.
  5. Swain ADC - 51.7% win rate with Seraphine Support (-1.0 points vs expected), 1,089 games.
  6. Corki ADC - 48.7% win rate with Seraphine Support (-0.8 points vs expected), 1,440 games.
  7. Aphelios ADC - 49.2% win rate with Seraphine Support (-0.7 points vs expected), 4,159 games.
  8. Varus ADC - 47.7% win rate with Seraphine Support (-0.7 points vs expected), 2,315 games.
  9. Xayah ADC - 52.0% win rate with Seraphine Support (-0.7 points vs expected), 3,802 games.
  10. Kalista ADC - 47.5% win rate with Seraphine Support (-0.6 points vs expected), 1,182 games.

Top 10 High Elo Seraphine Support all-role strongest synergies

  1. Vayne ADC - 52.1% win rate with Seraphine Support (+2.2 points vs expected), 1,669 games.
  2. Ashe ADC - 52.0% win rate with Seraphine Support (+2.1 points vs expected), 30,855 games.
  3. Rammus Jungle - 55.5% win rate with Seraphine Support (+1.9 points vs expected), 1,100 games.
  4. Tristana ADC - 51.9% win rate with Seraphine Support (+1.2 points vs expected), 3,325 games.
  5. Nunu & Willump Jungle - 50.3% win rate with Seraphine Support (+1.0 points vs expected), 1,391 games.
  6. Ezreal ADC - 47.6% win rate with Seraphine Support (+0.9 points vs expected), 10,636 games.
  7. Rek'Sai Jungle - 55.7% win rate with Seraphine Support (+0.9 points vs expected), 1,324 games.
  8. Amumu Jungle - 50.7% win rate with Seraphine Support (+0.8 points vs expected), 1,029 games.
  9. Vi Jungle - 50.8% win rate with Seraphine Support (+0.8 points vs expected), 3,051 games.
  10. Tahm Kench Top - 50.0% win rate with Seraphine Support (+0.7 points vs expected), 1,120 games.

Top 10 High Elo Seraphine Support all-role weakest synergies

  1. Gangplank Top - 48.9% win rate with Seraphine Support (-2.4 points vs expected), 3,684 games.
  2. Taliyah Jungle - 52.3% win rate with Seraphine Support (-2.2 points vs expected), 1,459 games.
  3. Zyra Jungle - 49.7% win rate with Seraphine Support (-1.8 points vs expected), 1,102 games.
  4. Samira ADC - 48.4% win rate with Seraphine Support (-1.7 points vs expected), 1,021 games.
  5. Lux ADC - 47.9% win rate with Seraphine Support (-1.6 points vs expected), 1,440 games.
  6. Miss Fortune ADC - 48.5% win rate with Seraphine Support (-1.5 points vs expected), 6,536 games.
  7. Nidalee Jungle - 50.4% win rate with Seraphine Support (-1.5 points vs expected), 2,001 games.
  8. Sion Top - 49.8% win rate with Seraphine Support (-1.5 points vs expected), 2,634 games.
  9. Ziggs ADC - 47.8% win rate with Seraphine Support (-1.4 points vs expected), 1,135 games.
  10. Graves Jungle - 48.5% win rate with Seraphine Support (-1.2 points vs expected), 6,016 games.

How these matchup statistics are calculated

Counter and synergy statistics use Ranked Solo/Duo games, exclude matches shorter than 600 seconds, and group results by patch window, region, rank scope, and champion role.

Pairwise pages use a rolling three-patch window and compare observed win rate with a log-odds expected win rate based on each champion's role-adjusted baseline; listed pairs require at least 1,000 games.

Read the full methodology for the model and guidance on interpreting these results.