Best Vayne Top Synergies

The best partner with Vayne Top is Malzahar Mid. The pair wins 50.9% across 1,929 games, 0.6 points more than the two champions' own win rates predict. Lissandra Mid (+0.5 over 1,176 games) and Smolder ADC (+0.5 over 1,401 games) also over-perform. Smolder ADC has the highest raw win rate (52.9%) among well-sampled pairs, but that is about what its own strength predicts (49.8% expected). Based on Low Elo Ranked Solo/Duo games, patches 26.20-26.22. These are observed associations, not guaranteed outcomes. The weakest listed synergies for Vayne Top are Yasuo Mid, Samira ADC, Yone Mid, Zed Mid, Aphelios ADC, Twitch ADC, Xayah ADC, Jinx ADC, Tristana ADC, and Master Yi Jungle. The detailed info below lists each partner with observed win rate, expected win rate delta, sample size, rank scope, and patch window.

Updated 2026-11-15. Data is current for LoL patch 26.22 (all regions, low elo and high elo).

Top 10 Low Elo Vayne Top all-role strongest synergies

  1. Malzahar Mid - 50.9% win rate with Vayne Top (+0.6 points vs expected), 1,929 games.
  2. Lissandra Mid - 52.0% win rate with Vayne Top (+0.5 points vs expected), 1,176 games.
  3. Smolder ADC - 52.9% win rate with Vayne Top (+0.5 points vs expected), 1,401 games.
  4. Lux Mid - 52.1% win rate with Vayne Top (+0.5 points vs expected), 1,186 games.
  5. Syndra Mid - 49.5% win rate with Vayne Top (+0.5 points vs expected), 1,704 games.
  6. Vex Mid - 49.8% win rate with Vayne Top (+0.4 points vs expected), 1,035 games.
  7. Galio Mid - 50.1% win rate with Vayne Top (+0.4 points vs expected), 1,376 games.
  8. Ashe ADC - 45.3% win rate with Vayne Top (+0.4 points vs expected), 2,154 games.
  9. Ezreal ADC - 45.1% win rate with Vayne Top (+0.4 points vs expected), 3,255 games.
  10. Veigar Mid - 49.5% win rate with Vayne Top (+0.4 points vs expected), 1,483 games.

Top 10 Low Elo Vayne Top all-role weakest synergies

  1. Yasuo Mid - 47.8% win rate with Vayne Top (-1.1 points vs expected), 2,618 games.
  2. Samira ADC - 45.4% win rate with Vayne Top (-1.0 points vs expected), 1,157 games.
  3. Yone Mid - 48.2% win rate with Vayne Top (-0.9 points vs expected), 2,594 games.
  4. Zed Mid - 45.5% win rate with Vayne Top (-0.8 points vs expected), 2,099 games.
  5. Aphelios ADC - 47.0% win rate with Vayne Top (-0.8 points vs expected), 1,429 games.
  6. Twitch ADC - 48.0% win rate with Vayne Top (-0.6 points vs expected), 1,391 games.
  7. Xayah ADC - 49.6% win rate with Vayne Top (-0.6 points vs expected), 1,423 games.
  8. Jinx ADC - 48.4% win rate with Vayne Top (-0.5 points vs expected), 3,470 games.
  9. Tristana ADC - 47.1% win rate with Vayne Top (-0.3 points vs expected), 2,124 games.
  10. Master Yi Jungle - 48.1% win rate with Vayne Top (-0.3 points vs expected), 2,324 games.

Top 10 High Elo Vayne Top all-role strongest synergies

  1. Syndra Mid - 47.1% win rate with Vayne Top (+0.5 points vs expected), 1,446 games.
  2. Viktor Mid - 49.6% win rate with Vayne Top (+0.3 points vs expected), 1,255 games.
  3. Lulu Support - 50.8% win rate with Vayne Top (+0.3 points vs expected), 2,197 games.
  4. Akali Mid - 49.7% win rate with Vayne Top (+0.2 points vs expected), 1,116 games.
  5. Nami Support - 49.8% win rate with Vayne Top (+0.1 points vs expected), 1,441 games.
  6. Jhin ADC - 49.8% win rate with Vayne Top (+0.1 points vs expected), 2,894 games.
  7. Jarvan IV Jungle - 50.8% win rate with Vayne Top (+0.1 points vs expected), 1,370 games.
  8. Aphelios ADC - 51.4% win rate with Vayne Top (+0.1 points vs expected), 1,274 games.
  9. Talon Jungle - 51.2% win rate with Vayne Top (+0.0 points vs expected), 1,032 games.
  10. Kha'Zix Jungle - 50.0% win rate with Vayne Top (+0.0 points vs expected), 1,104 games.

Top 10 High Elo Vayne Top all-role weakest synergies

  1. Yone Mid - 46.9% win rate with Vayne Top (-0.6 points vs expected), 1,156 games.
  2. Yasuo Mid - 47.4% win rate with Vayne Top (-0.6 points vs expected), 1,150 games.
  3. Zed Mid - 47.0% win rate with Vayne Top (-0.6 points vs expected), 1,095 games.
  4. Locke Mid - 47.7% win rate with Vayne Top (-0.4 points vs expected), 1,269 games.
  5. Sylas Mid - 45.4% win rate with Vayne Top (-0.4 points vs expected), 1,239 games.
  6. Katarina Mid - 50.0% win rate with Vayne Top (-0.3 points vs expected), 1,026 games.
  7. Nautilus Support - 48.0% win rate with Vayne Top (-0.3 points vs expected), 2,011 games.
  8. Thresh Support - 50.1% win rate with Vayne Top (-0.2 points vs expected), 2,289 games.
  9. Jinx ADC - 49.2% win rate with Vayne Top (-0.1 points vs expected), 1,751 games.
  10. Alistar Support - 51.7% win rate with Vayne Top (-0.1 points vs expected), 1,376 games.

How these matchup statistics are calculated

Counter and synergy statistics use Ranked Solo/Duo games, exclude matches shorter than 600 seconds, and group results by patch window, region, rank scope, and champion role.

Pairwise pages use a rolling three-patch window and compare observed win rate with a log-odds expected win rate based on each champion's role-adjusted baseline; listed pairs require at least 1,000 games.

Read the full methodology for the model and guidance on interpreting these results.