Best Karthus ADC Synergies

Compare Karthus ADC strongest and weakest synergies by duo win rate, expected win rate, delta, sample size, and allied role for team comp planning.

Updated 2026-06-16. Data is current for LoL patch 26.12 (all regions, low elo and high elo).

Top 5 High Elo Karthus ADC strongest synergies

  1. Nautilus Support - High Elo data: Karthus ADC vs Nautilus Support, 58.3% observed win rate, +4.6 percentage points vs expected, 666 games, 3-patch window 26.10-26.12.
  2. Zed Mid - High Elo data: Karthus ADC vs Zed Mid, 57.0% observed win rate, +2.8 percentage points vs expected, 512 games, 3-patch window 26.10-26.12.
  3. Graves Jungle - High Elo data: Karthus ADC vs Graves Jungle, 55.2% observed win rate, +1.8 percentage points vs expected, 556 games, 3-patch window 26.10-26.12.
  4. Senna Support - High Elo data: Karthus ADC vs Senna Support, 55.4% observed win rate, -0.1 percentage points vs expected, 599 games, 3-patch window 26.10-26.12.
  5. Nami Support - High Elo data: Karthus ADC vs Nami Support, 52.0% observed win rate, -1.5 percentage points vs expected, 850 games, 3-patch window 26.10-26.12.

Top 5 High Elo Karthus ADC weakest synergies

  1. Nami Support - High Elo data: Karthus ADC vs Nami Support, 52.0% observed win rate, -1.5 percentage points vs expected, 850 games, 3-patch window 26.10-26.12.
  2. Senna Support - High Elo data: Karthus ADC vs Senna Support, 55.4% observed win rate, -0.1 percentage points vs expected, 599 games, 3-patch window 26.10-26.12.
  3. Graves Jungle - High Elo data: Karthus ADC vs Graves Jungle, 55.2% observed win rate, +1.8 percentage points vs expected, 556 games, 3-patch window 26.10-26.12.
  4. Zed Mid - High Elo data: Karthus ADC vs Zed Mid, 57.0% observed win rate, +2.8 percentage points vs expected, 512 games, 3-patch window 26.10-26.12.
  5. Nautilus Support - High Elo data: Karthus ADC vs Nautilus Support, 58.3% observed win rate, +4.6 percentage points vs expected, 666 games, 3-patch window 26.10-26.12.