Best Lissandra Mid Synergies

The best partner with Lissandra Mid is Lucian ADC. The pair wins 52.2% across 5,923 games, 1.3 points more than the two champions' own win rates predict. Rengar Jungle (+1.3 over 2,582 games) and Master Yi Jungle (+1.2 over 7,499 games) also over-perform. Bel'Veth Jungle has the highest raw win rate (54.9%) among well-sampled pairs, but that is about what its own strength predicts (53.0% expected). Based on Low Elo Ranked Solo/Duo games, patches 26.20-26.22. These are observed associations, not guaranteed outcomes. The weakest listed synergies for Lissandra Mid are FiddleSticks Jungle, Zac Jungle, Lillia Jungle, Nidalee Jungle, Teemo Top, Amumu Jungle, Sejuani Jungle, Cho'Gath Jungle, Heimerdinger Top, and Ekko Jungle. The detailed info below lists each partner with observed win rate, expected win rate delta, sample size, rank scope, and patch window.

Updated 2026-11-15. Data is current for LoL patch 26.22 (all regions, low elo and high elo).

Lissandra Mid duo tips

  1. Viego & Lissandra - A nearby champion takedown can trigger both Viego's possession and Lissandra's Frozen Thrall, while Lissandra's reliable lockdown helps Viego secure the first kill that starts his reset chain.
  2. Darius & Lissandra - Lissandra's reliable engage and crowd control hold targets in place, giving Darius time to build Hemorrhage stacks and land Noxian Guillotine(R). If he gets the takedown, its reset lets him keep chaining through the fight.
  3. Lissandra & Lucian - Lissandra can immobilize a target with Ring of Frost(W) or Frozen Tomb(R), which triggers Lucian's Lightslinger(P) bonus attacks and gives him a window to follow with his burst. A Lissandra player specifically reports the Lucian pairing working for level 3 and level 6 picks.
  4. Lissandra & Draven - Lissandra supplies the lockdown Draven lacks: her W and R hold a target in place, giving his axe damage time to land, while Draven's W helps him follow and E can extend the slow after her control ends. A secured kill also cashes out League of Draven for extra gold, so Lissandra's mid-lane roams and skirmish setup can turn into the early snowball this pair relies on.
  5. Camille & Lissandra - Camille's Hookshot(E) can start a fight with a knock-up, and Hextech Ultimatum(R) keeps a priority target in its area; Lissandra can follow with Ring of Frost(W) or Frozen Tomb(R). Chaining their crowd control gives both champions time to land their burst on the same target.

Top 10 Low Elo Lissandra Mid all-role strongest synergies

  1. Lucian ADC - 52.2% win rate with Lissandra Mid (+1.3 points vs expected), 5,923 games.
  2. Rengar Jungle - 46.9% win rate with Lissandra Mid (+1.3 points vs expected), 2,582 games.
  3. Master Yi Jungle - 53.2% win rate with Lissandra Mid (+1.2 points vs expected), 7,499 games.
  4. Naafiri Jungle - 52.2% win rate with Lissandra Mid (+1.2 points vs expected), 2,498 games.
  5. Kha'Zix Jungle - 51.2% win rate with Lissandra Mid (+1.2 points vs expected), 4,604 games.
  6. Viego Jungle - 52.9% win rate with Lissandra Mid (+1.1 points vs expected), 7,179 games.
  7. Graves Jungle - 52.1% win rate with Lissandra Mid (+1.0 points vs expected), 6,080 games.
  8. Zed Jungle - 49.4% win rate with Lissandra Mid (+1.0 points vs expected), 2,158 games.
  9. Talon Jungle - 50.8% win rate with Lissandra Mid (+0.9 points vs expected), 3,250 games.
  10. Nocturne Jungle - 51.5% win rate with Lissandra Mid (+0.9 points vs expected), 4,708 games.

Top 10 Low Elo Lissandra Mid all-role weakest synergies

  1. FiddleSticks Jungle - 49.1% win rate with Lissandra Mid (-1.9 points vs expected), 1,283 games.
  2. Zac Jungle - 52.8% win rate with Lissandra Mid (-1.2 points vs expected), 1,435 games.
  3. Lillia Jungle - 51.6% win rate with Lissandra Mid (-1.1 points vs expected), 3,364 games.
  4. Nidalee Jungle - 47.2% win rate with Lissandra Mid (-1.0 points vs expected), 1,230 games.
  5. Teemo Top - 51.0% win rate with Lissandra Mid (-0.9 points vs expected), 4,634 games.
  6. Amumu Jungle - 52.7% win rate with Lissandra Mid (-0.8 points vs expected), 2,479 games.
  7. Sejuani Jungle - 50.6% win rate with Lissandra Mid (-0.8 points vs expected), 1,720 games.
  8. Cho'Gath Jungle - 52.7% win rate with Lissandra Mid (-0.7 points vs expected), 4,993 games.
  9. Heimerdinger Top - 50.0% win rate with Lissandra Mid (-0.7 points vs expected), 1,250 games.
  10. Ekko Jungle - 51.2% win rate with Lissandra Mid (-0.7 points vs expected), 2,473 games.

Top 10 High Elo Lissandra Mid all-role strongest synergies

  1. Viego Jungle - 52.2% win rate with Lissandra Mid (+1.3 points vs expected), 6,618 games.
  2. Samira ADC - 52.0% win rate with Lissandra Mid (+1.0 points vs expected), 2,341 games.
  3. Rengar Jungle - 50.1% win rate with Lissandra Mid (+0.9 points vs expected), 3,146 games.
  4. Kai'Sa ADC - 52.3% win rate with Lissandra Mid (+0.9 points vs expected), 15,594 games.
  5. Draven ADC - 53.0% win rate with Lissandra Mid (+0.9 points vs expected), 2,968 games.
  6. Kha'Zix Jungle - 52.0% win rate with Lissandra Mid (+0.8 points vs expected), 5,396 games.
  7. Graves Jungle - 52.5% win rate with Lissandra Mid (+0.8 points vs expected), 6,999 games.
  8. Master Yi Jungle - 53.2% win rate with Lissandra Mid (+0.7 points vs expected), 4,028 games.
  9. Kayn Jungle - 51.0% win rate with Lissandra Mid (+0.7 points vs expected), 4,247 games.
  10. Tristana ADC - 51.8% win rate with Lissandra Mid (+0.7 points vs expected), 5,722 games.

Top 10 High Elo Lissandra Mid all-role weakest synergies

  1. Taliyah Jungle - 51.5% win rate with Lissandra Mid (-1.3 points vs expected), 1,255 games.
  2. Viktor ADC - 49.5% win rate with Lissandra Mid (-1.1 points vs expected), 1,042 games.
  3. Ashe ADC - 47.7% win rate with Lissandra Mid (-1.0 points vs expected), 3,268 games.
  4. Smolder ADC - 47.8% win rate with Lissandra Mid (-0.9 points vs expected), 2,601 games.
  5. Zac Jungle - 49.9% win rate with Lissandra Mid (-0.9 points vs expected), 1,562 games.
  6. Varus ADC - 49.3% win rate with Lissandra Mid (-0.8 points vs expected), 2,172 games.
  7. Lillia Jungle - 51.0% win rate with Lissandra Mid (-0.7 points vs expected), 2,199 games.
  8. Elise Jungle - 51.9% win rate with Lissandra Mid (-0.6 points vs expected), 1,722 games.
  9. Kog'Maw ADC - 53.4% win rate with Lissandra Mid (-0.6 points vs expected), 1,509 games.
  10. Sejuani Jungle - 51.2% win rate with Lissandra Mid (-0.6 points vs expected), 1,045 games.

How these matchup statistics are calculated

Counter and synergy statistics use Ranked Solo/Duo games, exclude matches shorter than 600 seconds, and group results by patch window, region, rank scope, and champion role.

Pairwise pages use a rolling three-patch window and compare observed win rate with a log-odds expected win rate based on each champion's role-adjusted baseline; listed pairs require at least 1,000 games.

Read the full methodology for the model and guidance on interpreting these results.