Teemo & Irelia Synergy
Teemo Top and Irelia Mid win 53.5% of 2,365 Low Elo games together, +1.6 points vs expected, 2-patch window 26.19-26.20.
Researched on LoL patch 26.20. Tips are written to hold at any rank; stats come from Low Elo ranked games up to patch 26.20.
Why this duo works
Irelia supplies the hard crowd control and roaming follow-up that Teemo's kit lacks, while Teemo adds magic damage and slows that help her stay on marked targets. Teemo players recommend a roaming mid with reliable crowd control, which fits Irelia's stun and dash resets.
Playing the duo
Teemo's Noxious Trap (R) slows enemies, while Irelia's Flawless Duet (E) stuns and marks them; that mark gives Bladesurge (Q) a reset for her follow-up.
How to play as Teemo
Place mushrooms on river and jungle approaches before Irelia roams; if she catches someone with Flawless Duet (E), your slow and poison add follow-up damage while they are controlled.
How to play as Irelia
Use Flawless Duet (E) on an enemy already slowed by a mushroom, then follow the mark with Bladesurge (Q); Teemo's trap does not replace your own stun or mark.
Sources
These notes come from r/TeemoTalk, checked against the champions' abilities.