Teemo & Zed Synergy
Teemo Top and Zed Mid win 52.0% of 6,193 Low Elo games together, +1.1 points vs expected, 2-patch window 26.19-26.20.
Researched on LoL patch 26.20. Tips are written to hold at any rank; stats come from Low Elo ranked games up to patch 26.20.
Why this duo works
Teemo adds magic damage to Zed's physical burst, so opponents cannot rely on armor alone. Teemo's Noxious Trap(R) slow can also make it easier for Zed to land his full combo on a caught target.
Measured in High Elo: this duo wins 1.3pp more often than expected over 1,124 games.
Playing the duo
Teemo can provide the magic damage that an AD assassin team needs alongside Zed's physical burst, making a one-resistance defense less effective.
Noxious Trap(R) slows enemies, which gives Zed a better chance to land his full combo; Zed players value slows and other crowd control for that reason.
How to play as Teemo
Set Noxious Trap(R) around likely approach routes before Zed looks for a pick; if an opponent is slowed, Zed has an easier time landing his combo.
How to play as Zed
Use the pairing when your team needs magic damage alongside your physical burst; Teemo mains recommend AD assassins partly because Teemo can cover AP damage.
Sources
These notes come from r/TeemoTalk and r/zedmains, checked against the champions' abilities.