Best Annie Mid Synergies

The best partner with Annie Mid is Yasuo Top. The pair wins 49.8% across 1,235 games, 1.4 points more than the two champions' own win rates predict. Rengar Jungle (+1.4 over 1,062 games) and Fiora Top (+1.3 over 1,113 games) also over-perform. Based on Low Elo Ranked Solo/Duo games, patches 26.20-26.22. These are observed associations, not guaranteed outcomes. The weakest listed synergies for Annie Mid are Teemo Top, Mordekaiser Top, Ornn Top, Lillia Jungle, Malphite Top, Varus ADC, Cho'Gath Jungle, Amumu Jungle, Cho'Gath Top, and Shen Top. The detailed info below lists each partner with observed win rate, expected win rate delta, sample size, rank scope, and patch window.

Updated 2026-11-15. Data is current for LoL patch 26.22 (all regions, low elo and high elo).

Annie Mid duo tips

  1. Annie & Ezreal - When Pyromania(P) is ready, Annie's next offensive spell can stun; her ultimate can give Ezreal a brief opening to follow with his own burst.
  2. Sett & Annie - Annie can speed Sett into The Show Stopper(R) with Molten Shield(E), then follow his landing with a ready Pyromania(P) stun from Tibbers(R). That layered catch gives Sett time to add Facebreaker(E) and Haymaker(W) while the enemies are still controlled.

Top 10 Low Elo Annie Mid all-role strongest synergies

  1. Yasuo Top - 49.8% win rate with Annie Mid (+1.4 points vs expected), 1,235 games.
  2. Rengar Jungle - 48.9% win rate with Annie Mid (+1.4 points vs expected), 1,062 games.
  3. Fiora Top - 50.4% win rate with Annie Mid (+1.3 points vs expected), 1,113 games.
  4. Yone Top - 51.4% win rate with Annie Mid (+1.3 points vs expected), 2,585 games.
  5. Irelia Top - 54.0% win rate with Annie Mid (+1.3 points vs expected), 1,231 games.
  6. Samira ADC - 49.7% win rate with Annie Mid (+1.2 points vs expected), 1,473 games.
  7. Tryndamere Top - 48.9% win rate with Annie Mid (+1.1 points vs expected), 1,227 games.
  8. Kha'Zix Jungle - 50.3% win rate with Annie Mid (+1.1 points vs expected), 1,711 games.
  9. Viego Jungle - 51.0% win rate with Annie Mid (+0.9 points vs expected), 2,897 games.
  10. Graves Jungle - 51.7% win rate with Annie Mid (+0.9 points vs expected), 2,034 games.

Top 10 Low Elo Annie Mid all-role weakest synergies

  1. Teemo Top - 48.1% win rate with Annie Mid (-1.7 points vs expected), 1,960 games.
  2. Mordekaiser Top - 50.2% win rate with Annie Mid (-1.2 points vs expected), 2,282 games.
  3. Ornn Top - 50.5% win rate with Annie Mid (-1.2 points vs expected), 1,045 games.
  4. Lillia Jungle - 51.2% win rate with Annie Mid (-1.0 points vs expected), 1,368 games.
  5. Malphite Top - 50.0% win rate with Annie Mid (-0.9 points vs expected), 2,262 games.
  6. Varus ADC - 46.3% win rate with Annie Mid (-0.9 points vs expected), 1,158 games.
  7. Cho'Gath Jungle - 49.7% win rate with Annie Mid (-0.9 points vs expected), 2,047 games.
  8. Amumu Jungle - 50.4% win rate with Annie Mid (-0.8 points vs expected), 1,040 games.
  9. Cho'Gath Top - 50.9% win rate with Annie Mid (-0.5 points vs expected), 1,149 games.
  10. Shen Top - 47.4% win rate with Annie Mid (-0.5 points vs expected), 1,045 games.

Top 10 High Elo Annie Mid all-role strongest synergies

  1. Viego Jungle - 52.1% win rate with Annie Mid (+0.9 points vs expected), 1,937 games.
  2. Rengar Jungle - 51.7% win rate with Annie Mid (+0.8 points vs expected), 1,040 games.
  3. Kayn Jungle - 53.3% win rate with Annie Mid (+0.7 points vs expected), 1,440 games.
  4. Kha'Zix Jungle - 51.5% win rate with Annie Mid (+0.6 points vs expected), 1,661 games.
  5. Talon Jungle - 53.2% win rate with Annie Mid (+0.5 points vs expected), 1,580 games.
  6. Irelia Top - 53.3% win rate with Annie Mid (+0.5 points vs expected), 1,045 games.
  7. Master Yi Jungle - 51.1% win rate with Annie Mid (+0.4 points vs expected), 1,231 games.
  8. Tristana ADC - 52.5% win rate with Annie Mid (+0.4 points vs expected), 1,797 games.
  9. Garen Top - 53.0% win rate with Annie Mid (+0.4 points vs expected), 1,135 games.
  10. Fiora Top - 54.0% win rate with Annie Mid (+0.4 points vs expected), 1,103 games.

Top 10 High Elo Annie Mid all-role weakest synergies

  1. Ashe ADC - 48.4% win rate with Annie Mid (-0.3 points vs expected), 1,085 games.
  2. Cho'Gath Jungle - 49.1% win rate with Annie Mid (-0.3 points vs expected), 1,051 games.
  3. Leona Support - 50.2% win rate with Annie Mid (-0.2 points vs expected), 1,712 games.
  4. Malphite Top - 52.5% win rate with Annie Mid (-0.2 points vs expected), 1,473 games.
  5. Gangplank Top - 53.3% win rate with Annie Mid (-0.2 points vs expected), 1,121 games.
  6. Pyke Support - 49.7% win rate with Annie Mid (-0.2 points vs expected), 1,292 games.
  7. Nautilus Support - 49.2% win rate with Annie Mid (-0.2 points vs expected), 2,351 games.
  8. Hecarim Jungle - 50.1% win rate with Annie Mid (-0.1 points vs expected), 1,492 games.
  9. Xayah ADC - 52.4% win rate with Annie Mid (-0.1 points vs expected), 1,613 games.
  10. Rakan Support - 49.5% win rate with Annie Mid (-0.1 points vs expected), 1,077 games.

How these matchup statistics are calculated

Counter and synergy statistics use Ranked Solo/Duo games, exclude matches shorter than 600 seconds, and group results by patch window, region, rank scope, and champion role.

Pairwise pages use a rolling three-patch window and compare observed win rate with a log-odds expected win rate based on each champion's role-adjusted baseline; listed pairs require at least 1,000 games.

Read the full methodology for the model and guidance on interpreting these results.