Vayne & Blitzcrank Synergy

Vayne ADC and Blitzcrank Support win 46.8% of 2,513 Low Elo games together, -1.9 points vs expected, 2-patch window 26.19-26.20.

Researched on LoL patch 26.20. Tips are written to hold at any rank; stats come from Low Elo ranked games up to patch 26.20.

Playing the duo

Blitzcrank's hook and knock-up create time for Vayne to land repeated Silver Bolts(W) attacks; Vayne players say Blitz can help her survive the weak early lane and get room to auto.

How to play as Vayne

When Blitzcrank catches a target, use the knock-up window to get Silver Bolts(W) attacks in; avoid following if the hook would pull you into a bad early 2v2, since your lane needs time to scale.

How to play as Blitzcrank

Play around Vayne's early scaling and only force a hook when she can safely follow; Vayne mains describe her early lane as weak and value a support who gives her time and space to attack.

Sources

These notes come from r/vaynemains, checked against the champions' abilities.