Vayne ADC vs Pyke Support Matchup

Vayne ADC wins 54.2% of 2,323 Low Elo games against Pyke Support, +2.1 points vs expected, 2-patch window 26.19-26.20.

Researched on LoL patch 26.20. Tips are written to hold at any rank; stats come from Low Elo ranked games up to patch 26.20.

Why Vayne is favored

Vayne can use Tumble(Q) to sidestep Pyke's narrow hook and keep Condemn(E) to stop his Phantom Undertow(E) engage. If she avoids the first catch, she can punish him through an extended fight.

How to play as Vayne

Keep Tumble(Q) available to dodge Pyke's hook and save Condemn(E) for his dash. If he commits near a wall, use Condemn to interrupt him and set up a stun.

Tumble(Q) can reposition Vayne away from Pyke's Bone Skewer(Q), while Condemn(E) can knock back his Phantom Undertow(E) dash and stun him if it pushes him into terrain.

Vayne's Silver Bolts(W) deals true damage on every third hit, so Pyke cannot blunt her repeated-attack damage by building extra health.

How to play as Pyke

Bait out Vayne's Tumble(Q) before charging Bone Skewer(Q), and avoid engaging with Phantom Undertow(E) near terrain where she can Condemn you into a wall.

Sources

These notes come from r/pykemains, checked against the champions' abilities.