Vayne vs Ziggs ADC Matchup

Vayne ADC wins 50.5% of 586 Low Elo games against Ziggs ADC, +0.8 points vs expected, 2-patch window 26.19-26.20.

Researched on LoL patch 26.20. Tips are written to hold at any rank; stats come from Low Elo ranked games up to patch 26.20.

How to play as Vayne

Use Tumble(Q) to dodge Ziggs's Bouncing Bomb(Q), and accept being pushed rather than trading health for every minion; ADC players say Vayne can evade his poke but will usually give up push.

Farm patiently until your first item, then look for an extended fight when Ziggs missteps or has used Satchel Charge(W); players describe waiting for that opening rather than forcing an early all-in. (Unverified: no source confirms this note.)

Tumble(Q) lets Vayne reposition around Ziggs's skillshot poke, but it does not match his waveclear, so she can still be pushed toward her turret.

Sources

These notes come from r/ADCMains, checked against the champions' abilities.